CryoVeritas — Confidence in Color

Why CryoVeritas

Protect What Matters Most

The only temperature indicator that's user-activated, stores with samples down to −200 °C, and can be configured to signal breaches in as little as 5 minutes or as long as 48+ hours, truly mirroring how your specimens degrade.

Unique

User-Activated on Your Schedule

Unlike competitive indicators that start reacting at manufacture, CryoVeritas indicators remain dormant until you activate them. This eliminates false positives and gives you full control over monitoring start time.

100% shelf-stable until activated

Configurable

5 Minutes to 48+ Hours Response

Competitive products offer a single fixed response time, typically 5 minutes at the signal temperature. CryoVeritas indicators are tunable from 5 minutes to 48+ hours at the same threshold, matching the actual degradation kinetics of your specific specimens.

−200°C to ambient storage range

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Precision

Mirrors Real Specimen Degradation

DNA, RNA, proteins, and cells don't degrade instantly at a threshold. They follow time-dependent kinetics. CryoVeritas is the only indicator designed to mimic these degradation curves, giving you a biologically relevant signal instead of an arbitrary alarm.

GLP/GMP compliant & tamper-evident

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Why Time-at-Temperature Matters More Than Temperature Alone

A brief excursion to −60°C doesn't destroy an mRNA vaccine, but sustained exposure does. The same is true for extracted DNA, vitrified embryos, and CAR-T cell preparations. Damage is cumulative, following Arrhenius-type kinetics.

CryoVeritas indicators are engineered to integrate both time and temperature, providing a biologically meaningful signal that tells you whether your specimens are still viable, not just whether a freezer door was left open.

RNA Degradation Extracted RNA degrades rapidly above −60°C. Even brief thaw events cause hydrolysis of phosphodiester bonds, compromising sequencing and expression data.
DNA Fragmentation Genomic DNA stored at −80°C maintains integrity for decades, but repeated freeze-thaw cycles or extended warm excursions introduce strand breaks and oxidative damage.
Cell & Tissue Viability CAR-T cells, embryos, and stem cells require unbroken cryogenic chains. Ice recrystallization during partial thaws destroys membrane integrity and reduces post-thaw viability.

Built for Every Cold-Chain Application

From −196°C liquid nitrogen to −20°C distribution, CryoVeritas covers the full spectrum of critical temperature monitoring.

IVF & Reproductive Medicine

−196°C

Vitrified embryos, oocytes, sperm, and ovarian tissue require uninterrupted liquid nitrogen storage. A single warm excursion can trigger ice recrystallization and destroy viability.

EmbryosOocytesSpermOvarian tissue

Cell & Gene Therapy

−150 to −196°C

CAR-T cells, leukapheresis collections, and hematopoietic stem cells demand cryogenic storage. Interim −80°C holds must be monitored to maintain post-thaw viability and therapeutic efficacy.

CAR-T cellsStem cellsCord bloodMSCs

Vaccine Research & Distribution

−80 to −20°C

mRNA vaccines require ultra-cold storage at −80°C (Pfizer) or −20°C (Moderna) for months. Lipid nanoparticle integrity and RNA stability are directly tied to sustained temperature control.

mRNA vaccinesLNP formulationsViral vectors

Biobanking & Disease Research

−80 to −70°C

The workhorse of biorepositories. DNA, RNA, plasma, serum, CSF, and tumor biopsies all depend on −80°C to prevent nucleic acid hydrolysis, protein denaturation, and metabolite breakdown.

DNA/RNAPlasmaTumor tissueCSFBuffy coat

Blood Banking & Transfusion

−30 to −80°C

Fresh frozen plasma requires storage below −30°C for up to one year, and below −60°C for up to seven years. Rare-phenotype red blood cells are stored in glycerol at −65 to −80°C.

FFPCryoprecipitateFrozen RBCsPlatelet lysate

Forensics & Environmental Science

−80°C

Biological evidence integrity is critical for legal proceedings. Wildlife tissue archives, environmental DNA, and microbial community samples require verified ultra-cold chain documentation.

Forensic evidenceeDNAWildlife tissueMicrobiome

Confidence in Color