Research — CryoVeritas

Close-up of CryoVeritas temperature indicators showing clear and pink states

Our Origins

Born at the Borges Lab, Arizona State University

CryoVeritas technology originates from the laboratory of Prof. Chad Borges at the Biodesign Institute at Arizona State University. The Borges Lab specializes in developing novel chemical tools for analytical and bioanalytical applications, including tunable time-temperature indicators (TTIs) that form the foundation of every CryoVeritas product.

Years of fundamental research into thermochromic chemistry and reaction kinetics led to the development of indicators with precisely controllable signal temperatures and response times. This work enables visual cold-chain monitoring that is simple, accurate, and cost-effective.

Visit the Borges Lab Learn About TTI Research at the Borges Lab

From lab to market: CryoVeritas was co-founded by Prof. Chad Borges to bring this breakthrough technology out of the academic lab and into the hands of researchers, biobanks, and cold-chain professionals worldwide.

Featured Publication

Published in Chemical Engineering Journal

Peer-Reviewed Research Article

Tunable Time-Temperature Indicators for Cold-Chain Monitoring of Vaccines and Biospecimens

Journal Chemical Engineering Journal

Publisher Elsevier (ScienceDirect)

Year 2025

This publication presents the peer-reviewed science behind CryoVeritas indicators, detailing the novel thermochromic chemistry, tunable reaction kinetics, and validation data that demonstrate reliable visual detection of temperature excursions across a wide range of cold-chain conditions. The research establishes the foundation for cost-effective, non-reversible time-temperature indicators designed to protect vaccines, biologics, and biospecimens.

Read the Publication → Explore TTI Research

Key Innovations

Research-Driven Technology

Tunable Signal Temperatures

Precisely engineered chemistry allows each indicator to be tuned to a specific signal temperature, from 0 °C down to –67 °C and beyond, matching the exact requirements of your cold-chain.

Controllable Response Times

Reaction kinetics are fine-tuned so that indicators respond within calibrated timeframes: fast enough to detect dangerous excursions while avoiding false positives during routine handling.

Non-Reversible & Tamper-Evident

Once triggered, the color change is permanent and cannot be reversed, providing a trustworthy, tamper-evident record of temperature exposure that holds up to scrutiny.

The Science Behind CryoVeritas