Cryotube Product Line

Cryotube Signal™

In Development • Expected Late 2026

Cold-chain verification should travel with the sample, not live in a separate log. Cryotube Signal™ pairs a high-performance cryogenic storage tube with a built-in visual indicator, so each vial can show whether it remained below its defined threshold. Activate before storage, then check on retrieval: pink confirms protected storage, while clear flags a temperature excursion. It is a simpler, more direct way to screen critical samples the moment they leave the freezer.

2.0 mL

4.0 mL

Indicator on Every Tube

The temperature signal is integrated into the vial itself, so there is nothing extra to attach, charge, calibrate, or track.

Decision-Ready at Retrieval

When a vial comes out of storage, the readout is already there: pink indicates protected storage, while clear shows a heat excursion occurred.

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Key Features

A Cryogenic Tube That Carries Its Own Temperature Story

Cryotube Signal™ combines per-vial cold-chain visibility with the handling, sealing, and automation features labs already expect from a premium cryogenic tube.

Per-Vial Cold-Chain Visibility

CryoVeritas’ thermochromic indicator is built directly into the tube wall, giving each vial a simple visual record of whether storage conditions stayed within range. Activate it before storage, then read it whenever the sample is needed. No separate readers, attached tags, or external electronics are required.

One-step activation with no batteries, firmware, or calibration
Pink indicates the vial remained below threshold; clear indicates a heat excursion
Built with the same thermochromic platform used in the Pinktail BX™ line
Designed to function from –196 °C (vapor-phase LN₂) through ambient conditions

Faster Triage After a Storage Event

Facility alarms can tell you when a freezer drifted. Cryotube Signal helps show which individual vials may have been exposed. That makes it easier to review affected material quickly, preserve unaffected inventory, and focus follow-up decisions where they matter most.

Screen potentially compromised vials without sorting through system logs first
Reduce unnecessary disposal of samples that remained protected
Create per-vial evidence that supports internal review and external documentation

Engineered on a Secure Tube Platform

The indicator is paired with a robust cryogenic tube architecture designed for dependable sealing and repeatable handling. A co-molded PE/TPE screw cap removes the need for a separate o-ring, helping reduce contamination risk and simplifying use in demanding storage environments.

No separate o-ring to misplace, wear out, or interfere with sample protection
Vials and caps are fully autoclavable for lab workflows that require re-sterilization

Designed for Real Lab Throughput

Beyond cold-chain visibility, Cryotube Signal is built to fit the pace of modern sample handling. Each vial includes unique identification, clear writing space, printed graduations, and a star-socket cap compatible with automated capping and decapping systems. Self-standing geometry supports stable handling at the bench and in racks.

Unique barcode on each vial supports automated inventory and traceability
Star socket cap works with single, 8-channel, and full-rack decappers
Slim-profile cap geometry fits efficiently in standard cryoboxes and racks

Sustainability

Performance with a More Responsible Material Strategy

Cryotube Signal is being developed to pair cryogenic performance with material and manufacturing choices intended to reduce environmental impact.

Bio-Derived Tube Resin

The tube body uses bio-derived polypropylene sourced through more sustainable feedstock pathways, helping reduce dependence on conventional fossil-based inputs while preserving cryogenic durability.

Biologic-Ready Formulation

The resin formulation is intended for direct contact with vaccines and biologic materials, aligning material performance requirements with a more sustainable design approach.

Lower-Impact Manufacturing Approach

Manufacturing is being designed to reduce waste and energy demand, supporting a lower overall footprint than conventional cryogenic tube production methods.

Quality & Compliance

Quality Standards Built for Sensitive Samples

Cryotube Signal is being developed to meet the regulatory, purity, and manufacturing expectations laboratories place on high-value sample storage products.

Regulatory Certifications

Designed to align with widely used regulatory and transportation frameworks for diagnostic storage and movement of biological materials.

CE certified for diagnostic use
Conforms to IATA requirements for safe transportation of biological materials
Tamper-evident packaging ensures sterile barrier integrity through distribution

Biological Purity

Lot certification is designed to verify that the storage vessel itself does not introduce biological contaminants into sensitive workflows.

Lot certified human DNA-free, RNase-free, DNase-free, pyrogen-free, and ATP-free
Non-pyrogenic, non-cytotoxic, non-mutagenic
Heavy-metals free and BSE/TSE-free

Sterility Assurance

Sterilized by beta radiation to a sterility assurance level (SAL) of 10^–6, supporting the storage of sensitive biological samples, cell cultures, and primary isolates. Medical-grade raw materials are selected to maintain appearance and performance after re-sterilization.

Manufacturing Quality Control

Manufactured, assembled, and packaged in an ISO 7 (Class 10,000) cleanroom, with lot-level validation intended to support consistent sealing, cleanliness, and performance.

100% leak-testing performed during manufacturing to protect sample integrity
Lot-traceable documentation available for audit and compliance
Produced from medical-grade raw materials for long-term biocompatibility

Technical

Cryotube Signal™ Preliminary Specifications

Form Factor

Cryogenic storage tube with integrated indicator

Volume Range

2.0 mL & 4.0 mL

Tube Material

Eco-friendly bio-derived polypropylene

Cap Material

Co-molded PE screw cap with integrated TPE sealing layer (no separate o-ring)

Indicator Chemistry

Thermochromic (pink → clear on heat breach)

Operating Range

–196 °C (vapor-phase LN₂) to 50 °C

Cap Design

Slim profile with star socket for automated capping/decapping

Identification

Unique barcode per vial, white writing surface, printed graduations

Storage Formats

Self-standing; bulk bags, workstation racks, cryoboxes

Automation Compatible

Star socket for single, 8-channel, and full-rack decapping

Sterility

SAL 10^–6 (beta-irradiated)

Cleanroom

Manufactured & packaged in ISO 7 (Class 10,000)

Material Grade

Medical-grade; will not discolor after re-sterilization

Certifications

CE, IATA, human DNA-free, DNase/RNase-free, ATP-free, non-pyrogenic, non-cytotoxic, non-mutagenic, heavy-metals free, BSE/TSE-free

Autoclavable

Yes (vials and caps)

Packaging

Tamper-evident

Specifications are preliminary and subject to change as the product completes development. Final specs will be published upon release.